The Full form of CRF is Chronic Renal Failure. CRF is gradual loss of kidney function, with progressively more severe renal insufficiency until the stage called chronic irreversible kidney failure or end-stage renal disease. It is also known as Chronic Kidney Disease. In earlier days, there are typically no symptoms but later on, leg swelling, feeling tired, loss of appetite, vomiting or confusion may develop. Complications may include high blood pressure, heart disease, bone disease, or anemia. Any person can get CRF. Some people are more at risk than others. Some things that increase the risk for CRF include high blood pressure (hypertension), heart disease, diabetes, having a family member with kidney disease, being over 60 years old etc. Chronic Kidney Disease usually gets worse slowly over a period, and symptoms may not appear until your kidneys are badly damaged. A person may notice one or more of the following symptoms if his kidneys are beginning to fail i.e. Muscle cramps, Itching, Not feeling hungry, Nausea and vomiting, Swelling in feet and ankles, Too much urine (pee) or not enough urine, Trouble catching your breath and Trouble in sleeping. Having one or more of any of the symptoms above may be a sign of serious kidney problems and one should contact his doctor right away.