BINC Biology Syllabus –  Basic

Cell Biology


Basic aspects of Prokaryotic and eukaryotic cells (plant and animal cells); membranes and cellular compartments, cell organelles, structure and function

Cell motility and shape: cytoskeletal elements, cilia and flagella; motor proteins

Cell-cell interactions: Intercellular junctions

Photosynthesis, transportation of proteins in cells, transpiration, Electron transport chain

Cell cycle and its regulation; events during mitosis and meiosis

Genetics

Mendelian principles of inheritance, sex linked inheritance

Concept of linkage, linkage maps and recombination

Mutations – molecular, point and chromosomal mutations, hotspots

Phenotype and genotype relationships, role of environment, from gene to phenotype, gene interactions. Study of quantitative traits

Genetics of populations, genetics and evolution

Immunology

Immune systems: Innate and adaptive immunity in vertebrates

Antigen processing and presentation

Antibodies: Immunoglobulins, Immunoglobulin classes and subclasses, CDR and LDR regions and sequence numbering

Concepts of generation of diversity and specificity in immune system; Immunological methods

Molecular Biology

Prokaryotic genome organization and structure

Prokaryotic gene expression, factors involved in gene regulation

Eukaryotic genome organization and structure, Mechanism of gene expression in Eukaryotes, Basic mechanism of transcription and translation

Mechanisms by which genome undergoes changes, recombination, mutation, inversion, duplication, transposition

Biochemistry

Carbohydrates and lipids, their importance in cells

Proteins: Amino acids and their physiocochemical properties, peptide bond and peptides

Nucleic acids: nucleosides, nucleotides, RNA and DNA. Denaturation and renaturation of DNA

Enzymes: Units of activity, coenzymes and metal cofactors, temperature and pH effects, Michaelis-Menten kinetics, inhibitors and activators, active site

Organization of metabolic systems: enzyme chains, multienzyme complexes, multifunctional enzymes and regulatory enzymes

Concept of biochemical regulation, feed back and feed forward systems, biochemical oscillations

Bio-Informatics National Certification (BINC) 2019 Syllabus